Global Trade leader ecrobot

Jun 30 2025

Nintedanib sulfonate is a small molecule inhibitor of multi-receptor tyrosine kinases and non-receptor tyrosine kinases. It was first approved by the US FDA in 2014 and was first developed and sold by…

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Hangzhou ROYALL Import &...

China [CN]

Scince 2012

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Midostaurin

Jun 30 2025

Midotolin (MS) is an active derivative obtained through structural modification of staurosporine, an indolecarbazole alkaloid isolated from Marine Streptomycosis staurosporine culture medium in 1977. …

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Hangzhou ROYALL Import &...

China [CN]

Scince 2012

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Lapatinib

Jun 30 2025

lapatinib, trade name Tykerb, is an oral reversible small molecule tyrosine kinase inhibitor targeting HER-1/HER-2. Lapatinib has a different mechanism of action from the humanized monoclonal antibody…

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Hangzhou ROYALL Import &...

China [CN]

Scince 2012

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Vismodegib

Jun 30 2025

Vismodegib, trade name: Erivedge; It is one of the new anti-tumor drugs for the treatment of advanced cutaneous basal cell carcinoma (BCC), which was applied for and developed by Genentech Co., Ltd. a…

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Hangzhou ROYALL Import &...

China [CN]

Scince 2012

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Vandetanib

Jun 30 2025

Vandetanib is a once-daily oral inhibitor of vascular endothelial growth factor receptor 2 and epidermal growth factor receptor kinase activity.

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Hangzhou ROYALL Import &...

China [CN]

Scince 2012

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4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline

Jun 30 2025

4-chloro-6, 7-bis (2-methoxyethoxy) quinazoline is a common organosynthetic molecule that can be used as a molecular backbone to participate in the modification of bioactive molecules and drug molecul…

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Hangzhou ROYALL Import &...

China [CN]

Scince 2012

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Tucatinib

Jun 30 2025

Tukysa (Tucatinib)/Tucatinib (ONT-380) is an oral TKI(tyrosine kinase) inhibitor with high specificity for HER2. On April 17, 2020, the US FDA approved the combination of tucatinib with trastuzumab an…

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Hangzhou ROYALL Import &...

China [CN]

Scince 2012

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LOXO-195

Jun 30 2025

LOXO-195 is the next-generation TRK kinase inhibitor. The IC50 values of TRKA and TRKC are 0.6 nM and <2.5 nM, respectively.

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Hangzhou ROYALL Import &...

China [CN]

Scince 2012

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Larotrectinib Sulfate

Jun 30 2025

(3S)-N-[5-[(2R)-2-(2, 5-difluorophenyl) -1-pyrrolidine] pyrazole [1, 5-a] pyrimidine-3-yl] -3-hydroxy-1-pyrrolidine formamide sulfate is an effective and selective oral ATP-competitive inhibitor of my…

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Hangzhou ROYALL Import &...

China [CN]

Scince 2012

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Repotrectinib

Jun 30 2025

Lopsitinib (TPX-0005) is a fourth-generation ALK inhibitor developed by TPTherapeutics, founded by Dr. Cui Jingrong. It is a broad-spectrum ALK, ROS1 and TRK inhibitor, mainly targeting multiple acqui…

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Hangzhou ROYALL Import &...

China [CN]

Scince 2012

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X-376

Jun 30 2025

The second-generation ALK inhibitor enxatinib (X-396) is comprehensively superior to the first-generation crizotinib. Global multi-center Phase 3 clinical trials began in June 2016, and the approval f…

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Hangzhou ROYALL Import &...

China [CN]

Scince 2012

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Cabozantinib Malate

Jun 30 2025

Cabozantinib malate is a small molecule C-Met modulator. Cabozantinib malate can be used as an effective multi-target inhibitor of VEGFR2, Met, FLT3, Tie2, Kit and Ret. The IC50 values of cabozantinib…

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Hangzhou ROYALL Import &...

China [CN]

Scince 2012

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Crizotinib

Jun 30 2025

Crizotinib (XalkoriR), chemically known as 3-[(R)-1-(2, 6-dichloro-3-fluorophenyl) ethoxy]-5-[1-(piperidin-4-yl) -1H-pyrazole-4-yl Chemicalbook] pyridine-2-amine, is a white to light yellow powder in …

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Hangzhou ROYALL Import &...

China [CN]

Scince 2012

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Capmatinib

Jun 30 2025

Camatinib (INC280; INCB28060 is a potent, oral, selective, ATP-competitive c-Met kinase inhibitor (IC5Chemicalbook0=0.13nM). Camatinib can effectively inhibit the proliferation and migration of C-MET-…

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Hangzhou ROYALL Import &...

China [CN]

Scince 2012

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Lorlatinib

Jun 30 2025

Lorlatinib (PF-06463922) is an ALK inhibitor modified from Crizotinib by Pfizer of the United States. This drug entered clinical trials in 2014 for the treatment of lung cancer as described in Chemica…

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Hangzhou ROYALL Import &...

China [CN]

Scince 2012

Free Member