u-47700 u47700 powder white rose@overcomer-cn.com

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u-47700 u47700 powder white rose@overcomer-cn.com
Posting date : Jun 07, 2017
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Free Member Scince Jun 05, 2017
FOB Price
usd100
Min. Order Quantity
10g
Supply Abillity
1000kg per month
Port
door to door
Payment Terms
TT, MG, BTC
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according to your request
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Rose
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Product Detail
Company Info
 
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Place of Origin
China [CN]
Brand Name
skype rosechemical
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email rose@overcomer-cn.com
HS-CODE
3824-90
Package & Delivery Lead Time
Package
according to your request
Delivery Lead Time
arrange delivery within 1-2 business days after payment
Detailed Description

Overcomer Research Chemicals Co., Ltd is specialized in research chemicals. Our factory is located in Shanghai, China. Factoty has much production experience. And our export department was opened in year 2014.

 

Our company supply high quality products with the most competitive prices. If have any need or question, contact us freely. Hope we can have chance to build good long-term cooperation.

 

 

 

 

Brand Name: overcomerCAS No.: 82657-23-6Purity: 99.8%name: u-47700CAS: 82657-23-6Systematic (IUPAC) name: 3,4-Dichloro-N-[(1R,2R)-2-(dimethylamino)cyclohexyl]-N-methylbenzamideFormula: C16H22Cl2N2OMolar mass: 329.27Purity: 99.8form: powderdelivery: EMS, DHL, TNT, NL Post, HK Post, UPSpayment: WU, MG, Btc, TTskype: rosechemical

 

U-47700, street name pinky or pink, is an opioid analgesic drug developed by a team at Upjohn in the 1970s that acts as a selective agonist of the µ-opioid receptor with a Kd value of 5.3 nM compared to 910 nM for the κ-opioid receptor and has around 7.5 x the potency of morphine in animal models.

 

U-47700 is a structural isomer of the earlier opioid AH-7921 and the result of a great deal of work elucidating the quantitative structure–activity relationship of the scaffold. Upjohn looked for the key moieties which gave the greatest activity[8] and posted over a dozen patents on related compounds, each optimizing one moiety until they discovered that U-47700 was the most active.

 

U-47700 became the lead compound of selective kappa-opioid receptor ligands such as U-50488, U-51754 (containing a single methylene spacer difference) and U-69,593, which share very similar structures. Although not used medically, the selective kappa ligands are used in research.

 

Side effects

U-47700 has never been studied on humans, but would be expected to produce effects similar to those of other potent opioid agonists, including strong analgesia, sedation, euphoria, constipation, itching and respiratory depression which could be harmful or fatal. Tolerance and dependence would be expected to develop.

 

Combined consumption of U-47700 and fentanyl caused one fatality in Belgium. 17 opioid overdoses and several deaths in the USA had initially been associated with U-47700 in April 2016, as of September 2016 at least 15 fatalities were confirmed.

 

 

Superiority

1 Best service, high quality and reasonable price

2. It's customers' right to choose the package (EMS, DHL, FedEx, UPS);

3.It's customers' right to choose the packing way for his produccts from many recent effective packing ways

4.Specials are possible when client's order is big enough, including the discount policy;

5.Our company promise to deliver clients' package to his hands safely, or we'll cover the total loss and reship in time;

 

 

F.A.Q

1.How is the quality?

The qualities of most products are above 99% purity, same are 99.7% purity.

2.How is the package?

Aluminum foil bag or as customer's required.

3.How is the storage?

Keep in dry and cool place.

4.Do I need to pay extra for shipping cost?

No, our price includes the shipping cost already; you need not pay for any tax and others.

5.Can I order sample to test?

Yes, you are welcome to order sample before placing bulk order. We will send the sample directly to your door by courier.   

 

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Contact us

 

Email:  ROSE(@)OVERCOMER-CN.COM

Skype:  ROSECHEMICAL


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