TRANS-1,4-CYCLOHEXANEDIMETHANOL

China [CN]

I. Basic Information

Chinese Name: trans-1,4-Cyclohexanedimethanol

English Name: trans-1,4-Cyclohexanedimethanol

CAS Number: 3236-48-4

Molecular Formula: C₈H₁₆O₂

Molecular Weight: 144.21 (Calculated: C 66.63%, H 11.18%, O 22.19%)

II. Chemical Structure and Characteristics

Structural Analysis: The molecule is based on a cyclohexane nucleus, with a hydroxymethyl group (-CH₂OH) attached to each of the carbon atoms at positions 1 and 4. The two hydroxymethyl groups are in the trans position of the ring (i.e., located axially and equatorially, or vice versa, with opposite spatial orientations). Core Characteristics:

The trans configuration imparts a specific spatial structure to the molecule, resulting in greater symmetry and lower polarity compared to the cis isomer.

The cyclohexane ring is stabilized by a chair conformation, and the trans arrangement of the two hydroxymethyl groups reduces steric hindrance.

The molecule contains two primary hydroxyl groups (-CH₂OH), exhibiting typical alcohol reactivity.

III. Physical and Chemical Properties (Reference Data)

Appearance: Typically a white crystalline solid.

Melting Point: Approximately 113-117°C (the trans isomer has a higher melting point than the cis isomer, approximately 43-47°C, and can be distinguished by the melting point difference).

Boiling Point: Approximately 286°C (at atmospheric pressure), 160°C (10 mmHg, reduced pressure).

Solubility: Slightly soluble in water, soluble in polar organic solvents such as methanol, ethanol, and acetone, and has low solubility in non-polar solvents such as benzene and cyclohexane. Stability: Stable at room temperature, not easily oxidized, relatively stable to heat and light, and can undergo esterification or dehydration reactions when reacting with strong acids and strong bases.